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[livejournal.com profile] fannishly had this sitting around, and then her therapist recced it, so, here I am.

Kramer begins the book by explaining that nearly every single talk he's given about depression and depression medication has someone in the audience raising his/her hand and asking, "Well, what about Van Gogh?" The book is mainly to dispell the gulf between medical knowledge of depression versus common perception of what depression is and why people still believe it is an essential part of the human condition and/or a contributing factor to genius.

Kramer does a very convincing job detailing why depression is indeed a disease and why it should be eradicated. He manages to go into medical details on how depression damages the brain, especially the hippocampus, how it increases the risk for heart attacks, and in general how much damage it does to the body. He also managed to scare the heck out of me! I was reading and basically decided that I needed to go find a therapist rightthissecond, because I like my brain! I want to keep it healthy! Also, hardening arteries and minor strokes and all that jazz very not good!

Anyhow, I found this very convincing, but I also don't have enough medical background or general background on depression to really be able to evaluate how well he presents current research. It seemed to be fairly balanced, and he does remark that many of the studies he cites aren't conclusive.

He does discuss several things that rung true with me though -- take with a grain of salt, of course. He mentions that with some of his patients, when they hit baseline or normal or the undepressed state, whatever it's called, they know it. They feel fully themselves again, even if they've been suffering from depression for a very long time. I remember finally hitting baseline for the first time in two years in March and how right it felt, how I had no doubts that this is how I was supposed to feel. It's that more than anything that convinced me that depression is a disease, not the way the body and mind normally operate.

Of course, all Kramer's chapters on how the depressed mind and body looks very different from a healthy body in terms of resilience and health were also very convincing! And he also mentions something that I found very interesting, that depression is basically a disease that affects the body and mind's resilience. A depressed brain repairs damaged neurons and neuron casing (glial cells) much more slowly than a healthy brain; depression similarly hardens blood vessels and makes them more susceptible to rupture and blockage, ergo the heightened risks of stroke and heart disease. Kramer correlated this cellular susceptibility to damage with the depressed person's mental and psychological lack of resilience. I can't say on a scientific level how true that is, but it personally rings true.

An end to depression, he argues, would mean a return to "normal" functioning on a cellular level, along with psychological resilience. The gist of the book seems to be that while feeling sadness and grief and pain is part of the human condition and contributes to art and such, depression occurs when the body and the mind cannot bounce back from such emotions.

Anyhow, I probably didn't need much convincing with regard to such points, but it was convincing all the same. Highly recommended.

(no subject)

Sun, Sep. 11th, 2005 11:23 pm (UTC)
Posted by [identity profile] honorh.livejournal.com
Huh. I'll have to see if I can find that one on my weekly jaunt to B&N. If anything, I find that depression stifles my creativity, so I've never bought into the Van Gogh defense. Sure, going through depression and hard times can add up to some beautiful things, but if there's no end to it . . . people don't understand just how painful it is until they've been inside.

I remember vividly hitting baseline the first time I got on medication. I actually remarked to my mother, "This must be how normal people feel." People think medication numbs you, but it doesn't--depression does. Being able to feel something other than the depression? That's what baseline means to me.

(no subject)

Sun, Sep. 11th, 2005 11:34 pm (UTC)
Posted by [identity profile] yhlee.livejournal.com
It sounds interesting. I'll have to keep an eye out for it at the library.

(no subject)

Mon, Sep. 12th, 2005 12:00 am (UTC)
qiihoskeh: myo: kanji (Default)
Posted by [personal profile] qiihoskeh
For practically any mental illness, and some physical ones, it seems that there are different groups of doctors who define the name of the illness in quite different ways. I'm not sure what my point in saying this was ....

(no subject)

Mon, Sep. 12th, 2005 07:12 am (UTC)
Posted by [identity profile] superplin.livejournal.com
Thanks for the review: I've had this in my stack for months, but haven't yet got round to it. Nice to hear it's worth reading!

(no subject)

Mon, Sep. 12th, 2005 09:15 am (UTC)
Posted by [identity profile] fiveandfour.livejournal.com
Thanks. It's kind of ironic that I was just thinking the other day that I'm finally starting to feel like myself again and wondering if that meant I was "cured" or if once diagnosed as depressed one was forever depressed and had to stay on medication to keep from sinking back down. I'm definitely interested in reading this to help me figure out points of interest to discuss with my doctor. Funny how little accidents of timing like this occur...

(no subject)

Mon, Sep. 12th, 2005 11:45 am (UTC)
Posted by [identity profile] knullabulla.livejournal.com
On Van Gogh: I'm willing to bet that the guy was bipolar. Cause really, it just sounds far more manic to suddenly get it in your head that "oh, if I give her my ear, than she'll REALLY like me!" I mean, when you're depressed, you generally don't consider your body parts to be the bestest gifts ever--you're depressed and you suck and your ears suck (well, not literally. You'd probably end up with a lot of ear aches if they did).

Quite right about depression making you numb. I get smacked by hormones--put me on the pill and I become downright suicidal--so I haven't seen for myself how meds help, but I do trust your judgement on the matter.

(no subject)

Mon, Sep. 12th, 2005 12:46 pm (UTC)
Posted by [identity profile] flangirl.livejournal.com
Thanks for the review. I think I'll try and check this out from the library next time I go.

Not apropos of this post, but...

Tue, Sep. 13th, 2005 04:55 pm (UTC)
Posted by [identity profile] rachelmanija.livejournal.com
You two need to meet:

http://www.livejournal.com/users/octopedingenue/461555.html

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